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Found 8 Enz. Inhib. hit(s) with Target = 'Dihydrofolate reductase' and Ligand = 'BDBM50130950'
TargetDihydrofolate reductase(Escherichia coli)
Mcmaster University

LigandPNGBDBM50130950(5-(4-Chloro-phenylsulfanyl)-quinazoline-2,4-diamin...)
Affinity DataKi:  38nMAssay Description:Inhibition assay using Esherichia coli dihydrofolate reductase (DHFR). More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Escherichia coli)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50130950(5-(4-Chloro-phenylsulfanyl)-quinazoline-2,4-diamin...)
Affinity DataKi:  61nMAssay Description:Inhibition of Escherichia coli Dihydrofolate reductase in presence of 100 uM Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50130950(5-(4-Chloro-phenylsulfanyl)-quinazoline-2,4-diamin...)
Affinity DataKi:  61nMAssay Description:Inhibition of Escherichia coli Dihydrofolate reductase in presence of 100 uM Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50130950(5-(4-Chloro-phenylsulfanyl)-quinazoline-2,4-diamin...)
Affinity DataIC50:  320nMAssay Description:Inhibition constant against Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50130950(5-(4-Chloro-phenylsulfanyl)-quinazoline-2,4-diamin...)
Affinity DataIC50:  320nMAssay Description:Inhibition of Escherichia coli Dihydrofolate reductase in presence of 30 uM Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50130950(5-(4-Chloro-phenylsulfanyl)-quinazoline-2,4-diamin...)
Affinity DataIC50:  510nMAssay Description:Inhibition constant against Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50130950(5-(4-Chloro-phenylsulfanyl)-quinazoline-2,4-diamin...)
Affinity DataIC50:  510nMAssay Description:Inhibition of Escherichia coli Dihydrofolate reductase in presence of 100 uM Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50130950(5-(4-Chloro-phenylsulfanyl)-quinazoline-2,4-diamin...)
Affinity DataKd:  120nMAssay Description:Binding affinity to DHFR (unknown origin) by NMR analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed