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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dipeptidyl peptidase 4' and Ligand = 'BDBM50003987'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50003987
PNG
(CHEMBL3236108)
Show SMILES NC[C@H]1CN(C(=O)C[C@@H]1c1cc(F)ccc1F)c1ccc(nc1)C(F)(F)F
Show InChI InChI=1S/C18H16F5N3O/c19-11-1-3-15(20)14(5-11)13-6-17(27)26(9-10(13)7-24)12-2-4-16(25-8-12)18(21,22)23/h1-5,8,10,13H,6-7,9,24H2/t10-,13-/m0/s1
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MMDB

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Similars

Article
PubMed
n/an/a 443n/an/an/an/an/an/a



M.S. University of Baroda

Curated by ChEMBL


Assay Description
Inhibition of human DPP-4 expressed in baculovirus expression system using H-Gly-Pro-AMC as substrate after 30 mins by fluorometric analysis


Bioorg Med Chem Lett 24: 1918-22 (2014)


Article DOI: 10.1016/j.bmcl.2014.03.009
BindingDB Entry DOI: 10.7270/Q2G73G7F
More data for this
Ligand-Target Pair