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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor' and Ligand = 'BDBM50007513'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50007513
PNG
((R) N-(1-Benzyl-pyrrolidin-2-ylmethyl)-3-bromo-2,5...)
Show SMILES COc1cc(Br)c(OC)c(C(=O)NC[C@H]2CCCN2Cc2ccccc2)c1OC
Show InChI InChI=1S/C22H27BrN2O4/c1-27-18-12-17(23)20(28-2)19(21(18)29-3)22(26)24-13-16-10-7-11-25(16)14-15-8-5-4-6-9-15/h4-6,8-9,12,16H,7,10-11,13-14H2,1-3H3,(H,24,26)/t16-/m1/s1
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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.86E+3n/an/an/an/an/an/a



Astra Research Centre AB

Curated by ChEMBL


Assay Description
Inhibition of [3H]spiperone binding to rat striatal dopamine receptor D2 was determined in vitro


J Med Chem 34: 948-55 (1991)


Article DOI: 10.1021/jm00107a012
BindingDB Entry DOI: 10.7270/Q2GT5NS9
More data for this
Ligand-Target Pair