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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor' and Ligand = 'BDBM50007519'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50007519
PNG
((R) 3,5-Dichloro-N-[1-(4-fluoro-benzyl)-pyrrolidin...)
Show SMILES COc1c(Cl)cc(Cl)c(O)c1C(=O)NC[C@H]1CCCN1Cc1ccc(F)cc1
Show InChI InChI=1S/C20H21Cl2FN2O3/c1-28-19-16(22)9-15(21)18(26)17(19)20(27)24-10-14-3-2-8-25(14)11-12-4-6-13(23)7-5-12/h4-7,9,14,26H,2-3,8,10-11H2,1H3,(H,24,27)/t14-/m1/s1
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PC cid
PC sid
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Similars

Article
PubMed
n/an/a 21n/an/an/an/an/an/a



Astra Research Centre AB

Curated by ChEMBL


Assay Description
Inhibition of [3H]spiperone binding to rat striatal dopamine receptor D2 was determined in vitro


J Med Chem 34: 948-55 (1991)


Article DOI: 10.1021/jm00107a012
BindingDB Entry DOI: 10.7270/Q2GT5NS9
More data for this
Ligand-Target Pair