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Found 4 Enz. Inhib. hit(s) with Target = 'Dual specificity protein kinase TTK' and Ligand = 'BDBM241331'
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM241331(US10479788, Example 175 | US11046688, Example 175 ...)
Affinity DataIC50:  2nMpH: 7.0 T: 2°CAssay Description:The enzyme reaction (total volume 10 μl) was carried out in black 384-well low volume plates containing full length MPS1 (12.5 nM or 3 nM), fluo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM241331(US10479788, Example 175 | US11046688, Example 175 ...)
Affinity DataIC50:  2nMAssay Description:The enzyme reaction (total volume 10 μl) was carried out in black 384-well low volume plates containing full length MPS1 (12.5 nM or 3 nM), fluo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM241331(US10479788, Example 175 | US11046688, Example 175 ...)
Affinity DataIC50:  2nMAssay Description:The enzyme reaction (total volume 10 μl) was carried out in black 384-well low volume plates containing full length MPS1 (12.5 nM or 3 nM), fluo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM241331(US10479788, Example 175 | US11046688, Example 175 ...)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of MPS1 autophosphorylation at Thr33/Ser37 in human HCT116 cells after 2 hrs by MSD assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed