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Found 3 Enz. Inhib. hit(s) with Target = 'E3 ubiquitin-protein ligase Mdm2' and Ligand = 'BDBM50014094'
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50014094(CHEMBL3260849)
Affinity DataKi:  600nMAssay Description:Binding affinity to MDM2 (unknown origin) assessed as inhibition of interaction with p53More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50014094(CHEMBL3260849)
Affinity DataKi:  600nMAssay Description:Displacement of 5'FAM-LTFEHYWAQLTS from human recombinant N-terminal domain of MDM2 (1 to 118 residues) expressed in Escherichia coli BL21 (DE3) cell...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50014094(CHEMBL3260849)
Affinity DataKi:  600nMAssay Description:Inhibition of fluorescent P4 peptide binding to human MDM2 (18 to 111 or 1 to 125 residues) expressed in Escherichia coli BL21(DE3) Rosetta measured ...More data for this Ligand-Target Pair