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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'EDNRA' and Ligand = 'BDBM50085832'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
EDNRA


(RAT)
BDBM50085832
PNG
(CHEMBL171513 | [2-Cyano-5-(2-fluoro-pyridin-4-ylme...)
Show SMILES Cc1ccccc1C(Oc1cc(OCc2ccnc(F)c2)ccc1C#N)C(O)=O
Show InChI InChI=1S/C22H17FN2O4/c1-14-4-2-3-5-18(14)21(22(26)27)29-19-11-17(7-6-16(19)12-24)28-13-15-8-9-25-20(23)10-15/h2-11,21H,13H2,1H3,(H,26,27)
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UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 23n/an/an/an/an/an/a



Rhône-Poulenc Rorer

Curated by ChEMBL


Assay Description
In vitro ability to antagonise the binding of [125I]-ET-1 to the rat aortic A10 cell membrane endothelin A receptor.


J Med Chem 43: 900-10 (2000)


Article DOI: 10.1021/jm990378b
BindingDB Entry DOI: 10.7270/Q2154G73
More data for this
Ligand-Target Pair