Compile Data Set for Download or QSAR
maximum 50k data
Found 7 Enz. Inhib. hit(s) with Target = 'Ectonucleotide pyrophosphatase/phosphodiesterase family member 2' and Ligand = 'BDBM50300214'
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Memphis

Curated by ChEMBL
LigandPNGBDBM50300214(2-(4-((3,5-dichlorophenyl)carbamothioyl)piperazin-...)
Affinity DataKi:  1.90E+3nMAssay Description:Competitive inhibition of human autotaxin at free state isolated from MDA-MB-231 cells assessed as blockade of FS3 substrate hydrolysis by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Memphis

Curated by ChEMBL
LigandPNGBDBM50300214(2-(4-((3,5-dichlorophenyl)carbamothioyl)piperazin-...)
Affinity DataKi:  1.90E+3nMAssay Description:Competitive-type inhibition of autotaxin-mediated FS3 hydrolysis by Michaelis-Menton analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Memphis

Curated by ChEMBL
LigandPNGBDBM50300214(2-(4-((3,5-dichlorophenyl)carbamothioyl)piperazin-...)
Affinity DataKi:  6.50E+3nMAssay Description:Noncompetitive inhibition of autotaxin-mediated pNP-TMP hydrolysis by Michaelis-Menton analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Memphis

Curated by ChEMBL
LigandPNGBDBM50300214(2-(4-((3,5-dichlorophenyl)carbamothioyl)piperazin-...)
Affinity DataKi:  6.50E+3nMAssay Description:Noncompetitive inhibition of autotaxin-mediated pNP-TMP hydrolysis by Michaelis-Menton analysis for enzyme-substrate complexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Memphis

Curated by ChEMBL
LigandPNGBDBM50300214(2-(4-((3,5-dichlorophenyl)carbamothioyl)piperazin-...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of autotaxin-mediated pNP-TMP hydrolysis in human MDA-MB-435 cells by amplex red protocolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Memphis

Curated by ChEMBL
LigandPNGBDBM50300214(2-(4-((3,5-dichlorophenyl)carbamothioyl)piperazin-...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of autotaxin-mediated FS3 hydrolysis in human MDA-MB-435 cells by amplex red protocolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Memphis

Curated by ChEMBL
LigandPNGBDBM50300214(2-(4-((3,5-dichlorophenyl)carbamothioyl)piperazin-...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of human autotaxin isolated from MDA-MB-231 cells assessed as blockade of FS3 substrate hydrolysis by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed