Compile Data Set for Download or QSAR
Found 1 Enz. Inhib. hit(s) with Target = 'Egl nine homolog 1' and Ligand = 'BDBM93416'
TargetEgl nine homolog 1(Homo sapiens (Human))
Amgen Inc

LigandPNGBDBM93416(PHD Inhibitor, 8{6})
Show SMILES CC(=O)N[C@@H](CC(O)=O)C(=O)NCc1ccc2n(C)c(=O)c(C(=O)NCC(O)=O)c(O)c2c1
Show InChI InChI=1S/C20H22N4O9/c1-9(25)23-12(6-14(26)27)18(31)21-7-10-3-4-13-11(5-10)17(30)16(20(33)24(13)2)19(32)22-8-15(28)29/h3-5,12,30H,6-8H2,1-2H3,(H,21,31)(H,22,32)(H,23,25)(H,26,27)(H,28,29)/t12-/m0/s1
Affinity DataIC50: 138nMAssay Description:PHD1,2,3 activity was measured utilizing homogeneous time-resolved fluroescence energy transfer techology by detecting the trans-4-hydroxylatio of HI...More data for this Ligand-Target Pair