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Found 2 Enz. Inhib. hit(s) with Target = 'Endothelin-1 receptor' and Ligand = 'BDBM50034441'
TargetEndothelin-1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50034441(5-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-naphthalen...)
Affinity DataIC50:  1.30E+4nMAssay Description:Ability to inhibit [125I]-ET1 binding to vascular smooth muscle (vsm)- A10 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50034441(5-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-naphthalen...)
Affinity DataIC50:  1.30E+4nMAssay Description:Antagonism of [125 I]ET-1 binding to the rat endothelin receptor in vascular smooth muscle VSM-A10 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed