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Found 2 Enz. Inhib. hit(s) with Target = 'Endothelin-1 receptor' and Ligand = 'BDBM50050794'
TargetEndothelin-1 receptor(Homo sapiens (Human))
Prestwick Chemical

Curated by ChEMBL
LigandPNGBDBM50050794(2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-methoxy-3,3-...)
Affinity DataKi:  6nMAssay Description:Binding affinity against human Endothelin A receptor; orally active in vivo at 30 mg/kg, poMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Prestwick Chemical

Curated by ChEMBL
LigandPNGBDBM50050794(2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-methoxy-3,3-...)
Affinity DataKi:  6nMAssay Description:Binding affinity of the compound towards human Endothelin A receptor by measuring its ability to displace [125I]-ET-1 from CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed