Found 20 Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM112499' 
Affinity DataIC50: 0.630nMAssay Description:Inhibition of EGFR exon 19 deletion activating mutant phosphorylation in human PC9 cells after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 0.640nMAssay Description: This assay quantifies the phosphorylation of EGFR at Tyr1068 and was used to measure the inhibitory effect of compounds on the transgenic EGFR del19...More data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Inhibition of EGFR (unknown origin) by ELISA methodMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of GST-tagged human EGFR catalytic domain expressed in insect cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of GST-tagged EGFR expressed in sf9 cells by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Irreversible inhibition of full length human ERBB1 autophosphorylation transfected in EGF-stimulated mouse NIH/3T3 cells incubated for 2 hrs followed...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Irreversible inhibition of GST-tagged ERBB1 (unknown origin) (Met-668 to Ala-1211 residues) expressed in baculovirus infected Sf9 insect cells assess...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of EGFR in human A431 cells assessed as reduction in EGF-stimulated EGFR autophosphorylation preincuabted for 90 mins followed by EGF-stim...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of EGFR phosphorylation (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of human GST-fused EGFR kinase domain expressed in baculovirus expression system measured after 30 mins by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of EGFR (unknown origin) expressed in insect cells by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of GST-tagged EGFR (unknown origin) expressed in insect cells by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 6.90nMpH: 7.4 T: 2°CAssay Description:Inhibition of erbB tyrosine kinase activity was assessed using an ELISA-based receptor tyrosine kinase assay. Kinase reactions (50 mM HEPES, pH 7.4, ...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of wild type EGFR phosphorylation in human LoVo cells after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Inhibition of EGFR L858R/T970M double mutant phosphorylation in human NCI-H1975 cells after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 440nMAssay Description:Inhibition of EGFR L858R/T790M mutant (unknown origin) in human NCI-H1975 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 22nMAssay Description:Inhibition of EGF-stimulated wild-type EGFR phosphorylation in human A-431 cells incubated for 2 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataEC50: 40nMAssay Description:Inhibition of EGFR T790M mutant phosphorylation in human NCI-H1975 cells incubated for 2 hrs by ELISAMore data for this Ligand-Target Pair
