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Found 5 Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM4304'
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University Of Jerusalem

LigandPNGBDBM4304((2E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-phenylprop-...)
Affinity DataIC50:  700nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University Of Jerusalem

LigandPNGBDBM4304((2E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-phenylprop-...)
Affinity DataIC50:  700nMAssay Description:Inhibition of EGFR in human A431 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University Of Jerusalem

LigandPNGBDBM4304((2E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-phenylprop-...)
Affinity DataIC50:  1.25E+3nMAssay Description:Inhibition of Epidermal growth factor receptor autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University Of Jerusalem

LigandPNGBDBM4304((2E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-phenylprop-...)
Affinity DataIC50:  1.26E+3nMAssay Description:Inhibitory activity against epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University Of Jerusalem

LigandPNGBDBM4304((2E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-phenylprop-...)
Affinity DataIC50:  1.00E+4nMpH: 7.5 T: 2°CAssay Description:The assay was using Swiss 3T3 cell membranes harboring EGF-R or PDGFR-beta. Receptor autophosphorylation was initiated by addition of [gamma-32P]ATP ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed