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Found 3 Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM50157909'
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50157909(CHEMBL3781897)
Affinity DataKi:  15nMAssay Description:Inhibition of human EGFR catalytic domain (668 to 1210 residues) T790M/L858R double mutant using Fl-EEPLYWSFPAKKK-CONH2 peptide substrate preincubate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50157909(CHEMBL3781897)
Affinity DataKi:  634nMAssay Description:Inhibition of human N-terminal GST-tagged EGFR catalytic domain (669 to 1210 residues) expressed in baculovirus expression system using Fl-EEPLYWSFPA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50157909(CHEMBL3781897)
Affinity DataEC50:  433nMAssay Description:Inhibition of EGFR T790M/L858R double mutant phosphorylation in human H1975 cells preincubated for 1 hr followed by EGF stimulation for 8 mins by ele...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed