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Found 4 Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM50171520'
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171520((E)-4-Dimethylamino-but-2-enoic acid [4-(4,5-dichl...)
Affinity DataIC50:  0.110nMAssay Description:Inhibition of EGF Receptor autophosphorylation in A431 cell lysateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171520((E)-4-Dimethylamino-but-2-enoic acid [4-(4,5-dichl...)
Affinity DataIC50:  4nMAssay Description:Inhibition of HER1 kinase in intact DHER14 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171520((E)-4-Dimethylamino-but-2-enoic acid [4-(4,5-dichl...)
Affinity DataIC50:  10nMAssay Description:Inhibition of EGF Receptor autophosphorylation in A431 cell lysate; Range = 4-10 nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171520((E)-4-Dimethylamino-but-2-enoic acid [4-(4,5-dichl...)
Affinity DataIC50:  50nMAssay Description:Inhibition of EGF Receptor autophosphorylation in A431 cell lysate; Range = 10-50 nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed