BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'GABA receptor alpha-1 subunit' and Ligand = 'BDBM50001562'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
GABA receptor alpha-1 subunit


(Mus musculus)
BDBM50001562
PNG
(5-(6-Imino-3-phenyl-6H-pyridazin-1-ylmethyl)-isoxa...)
Show SMILES N=c1ccc(nn1Cc1cc(=O)[nH]o1)-c1ccccc1
Show InChI InChI=1S/C14H12N4O2/c15-13-7-6-12(10-4-2-1-3-5-10)16-18(13)9-11-8-14(19)17-20-11/h1-8,15H,9H2,(H,17,19)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 240n/an/an/an/an/an/a



Centre de Neurochimie du CNRS

Curated by ChEMBL


Assay Description
Affinity for gamma-aminobutyric-acid A receptor measured by its ability to displace [3H]gabazine antagonist from rat brain preparations.


J Med Chem 35: 4092-7 (1992)


Article DOI: 10.1021/jm00100a015
BindingDB Entry DOI: 10.7270/Q25X29J4
More data for this
Ligand-Target Pair