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Found 2 Enz. Inhib. hit(s) with Target = 'Genome polyprotein' and Ligand = 'BDBM403660'
TargetGenome polyprotein(Hepatitis C virus genotype 3a (isolate k3a) (HCV))
Gilead Pharmasset

US Patent
LigandPNGBDBM403660((1aS,2aR,6S,9S,10S,11R,23aR,23bS)-6-tert-butyl-N-[...)
Affinity DataKi:  0.0500nMAssay Description:Purified NS3 protease domain (amino acids 1-181) of the genotype 1b and 3a virus were generated as above. The internally quenched fluorogenic depsipe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Gilead Pharmasset

US Patent
LigandPNGBDBM403660((1aS,2aR,6S,9S,10S,11R,23aR,23bS)-6-tert-butyl-N-[...)
Affinity DataKi:  0.0500nMAssay Description:Purified NS3 protease domain (amino acids 1-181) of the genotype 1b and 3a virus were generated as above. The internally quenched fluorogenic depsipe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent