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Found 2 Enz. Inhib. hit(s) with Target = 'Genome polyprotein [2420-3010]' and Ligand = 'BDBM243477'
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandPNGBDBM243477(US9427440, 25)
Affinity DataKon:  0.000310M-1s-1 Koff:  2.90E+4s-1pH: 7.4 T: 2°CAssay Description:All measurements were performed on a Biacore T100 instrument (GE Healthcare). The purified HIS6-tagged NS5BΔC21 polymerases were immobilized us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland

US Patent
LigandPNGBDBM243477(US9427440, 25)
Affinity DataKd:  11nMpH: 7.4 T: 2°CAssay Description:All measurements were performed on a Biacore T100 instrument (GE Healthcare). The purified HIS6-tagged NS5BΔC21 polymerases were immobilized us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent