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Found 4 Enz. Inhib. hit(s) with Target = 'Glucocorticoid receptor' and Ligand = 'BDBM50440215'
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ironwood Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50440215(CHEMBL2426649)
Affinity DataKi:  4nMAssay Description:Binding affinity to glucocorticoid receptor (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ironwood Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50440215(CHEMBL2426649)
Affinity DataEC50: >1.00E+4nMAssay Description:Transactivation of glucocorticoid receptor ligand binding domain (unknown origin) transfected in human HeLa cells assessed as activation of NP-1 by G...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ironwood Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50440215(CHEMBL2426649)
Affinity DataEC50:  185nMAssay Description:Agonist activity at glucocorticoid receptor in human A549 cells assessed as inhibition of IL-1beta-induced NF-kappaB dependent E-selectin activation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ironwood Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50440215(CHEMBL2426649)
Affinity DataEC50:  349nMAssay Description:Agonist activity at glucocorticoid receptor in human A549 cells assessed as inhibition of PMA-induced AP-1 activation by luciferase reporter gene ass...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed