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Found 5 Enz. Inhib. hit(s) with Target = 'Glutamate receptor ionotropic, kainate 2' and Ligand = 'BDBM50207594'
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207594(2,3-Dihydroxy-6-nitro-benzo[f]quinoxaline-7-sulfon...)
Affinity DataKi:  1.32E+4nMAssay Description:Inhibition of [3H]-KA binding to iontropic glutamate receptor 6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207594(2,3-Dihydroxy-6-nitro-benzo[f]quinoxaline-7-sulfon...)
Affinity DataKi:  1.32E+4nMAssay Description:Ability to displace binding of [3H]AMPA to recombinant human AMPA receptor Ionotropic glutamate receptor ionotropic kainate 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207594(2,3-Dihydroxy-6-nitro-benzo[f]quinoxaline-7-sulfon...)
Affinity DataKi: >1.00E+5nMAssay Description:Ability to displace binding of [3H]KA to recombinant human KA receptor Ionotropic glutamate receptor ionotropic kainate 2 expressed in EK 293 cell me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207594(2,3-Dihydroxy-6-nitro-benzo[f]quinoxaline-7-sulfon...)
Affinity DataIC50:  2.90E+4nMAssay Description:Inhibition of glutamate-induced calcium influx in HEK293 cells expressing human GLUK6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207594(2,3-Dihydroxy-6-nitro-benzo[f]quinoxaline-7-sulfon...)
Affinity DataIC50:  2.90E+4nMAssay Description:Antagonist activity at human recombinant GLUK6 expressed in HEK293 cells assessed as inhibition of glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed