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Found 1 Enz. Inhib. hit(s) with Target = 'Guanylate cyclase soluble subunit alpha-1' and Ligand = 'BDBM280817'
TargetGuanylate cyclase soluble subunit alpha-1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM280817((S)-3-(2-{4-amino-2-[6- chloro-1-(2- fluorobenzyl)...)
Affinity DataKi:  0.0600nMpH: 7.4Assay Description:The binding potencies of sGC compounds to the human recombinant sGC enzyme were determined in a Size Exclusion Chromatography (SEC) competition bindi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent