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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'HMG-CoA reductase' and Ligand = 'BDBM50007259'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
HMG-CoA reductase


(Rattus norvegicus (rat))
BDBM50007259
PNG
(CHEMBL316899 | Sodium; 6-{2-[3-(4-fluoro-phenoxy)-...)
Show SMILES Cc1cccc(CCCOc2ccc(F)cc2)c1OCC(O)C[C@@H](O)CC([O-])=O
Show InChI InChI=1S/C22H27FO6/c1-15-4-2-5-16(6-3-11-28-20-9-7-17(23)8-10-20)22(15)29-14-19(25)12-18(24)13-21(26)27/h2,4-5,7-10,18-19,24-25H,3,6,11-14H2,1H3,(H,26,27)/p-1/t18-,19?/m1/s1
PDB
MMDB

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Similars

Article
PubMed
n/an/a 250n/an/an/an/an/an/a



Hoechst AG

Curated by ChEMBL


Assay Description
In vitro inhibition of HMG-CoA reductase in solubilized rat liver.


J Med Chem 34: 2962-83 (1991)


Article DOI: 10.1021/jm00114a004
BindingDB Entry DOI: 10.7270/Q2C829WX
More data for this
Ligand-Target Pair