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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'HMG-CoA reductase' and Ligand = 'BDBM50007297'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
HMG-CoA reductase


(Rattus norvegicus (rat))
BDBM50007297
PNG
(CHEMBL2367825 | Sodium; 7-(3,5-dichloro-4'-fluoro-...)
Show SMILES [Na+].O[C@H](C[C@H](O)\C=C\c1c(Cl)cc(Cl)cc1-c1ccc(F)cc1)CC([O-])=O
Show InChI InChI=1S/C19H17Cl2FO4.Na/c20-12-7-17(11-1-3-13(22)4-2-11)16(18(21)8-12)6-5-14(23)9-15(24)10-19(25)26;/h1-8,14-15,23-24H,9-10H2,(H,25,26);/q;+1/p-1/b6-5+;/t14-,15-;/m1./s1
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MMDB

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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.5n/an/an/an/an/an/a



Hoechst AG

Curated by ChEMBL


Assay Description
In vitro inhibition of solubilized HMG-CoA reductase in rat liver.


J Med Chem 34: 2962-83 (1991)


Article DOI: 10.1021/jm00114a004
BindingDB Entry DOI: 10.7270/Q2C829WX
More data for this
Ligand-Target Pair