BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'HMG-CoA reductase' and Ligand = 'BDBM50007307'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
HMG-CoA reductase


(Rattus norvegicus (rat))
BDBM50007307
PNG
(CHEMBL101806 | Sodium; 6-(2,4-dichloro-6-cyclohexa...)
Show SMILES OC(COc1c(Cl)cc(Cl)cc1C(=O)C1CCCCC1)C[C@@H](O)CC([O-])=O
Show InChI InChI=1S/C19H24Cl2O6/c20-12-6-15(18(26)11-4-2-1-3-5-11)19(16(21)7-12)27-10-14(23)8-13(22)9-17(24)25/h6-7,11,13-14,22-23H,1-5,8-10H2,(H,24,25)/p-1/t13-,14?/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 190n/an/an/an/an/an/a



Hoechst AG

Curated by ChEMBL


Assay Description
In vitro inhibition of HMG-CoA reductase in solubilized rat liver.


J Med Chem 34: 2962-83 (1991)


Article DOI: 10.1021/jm00114a004
BindingDB Entry DOI: 10.7270/Q2C829WX
More data for this
Ligand-Target Pair