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Found 2 Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Ligand = 'BDBM24758'
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Amgen

LigandPNGBDBM24758(2-benzyl-5-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]-3-...)
Affinity DataKi:  489nM ΔG°:  -35.7kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Amgen

LigandPNGBDBM24758(2-benzyl-5-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]-3-...)
Affinity DataIC50:  489nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed