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Found 4 Enz. Inhib. hit(s) with Target = 'High affinity nerve growth factor receptor' and Ligand = 'BDBM164912'
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Genzyme

US Patent
LigandPNGBDBM164912(US10166239, Ex. 3-20 | US11406644, Example 3-20 | ...)
Affinity DataIC50:  0.900nMpH: 7.5 T: 2°CAssay Description:Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Genzyme

US Patent
LigandPNGBDBM164912(US10166239, Ex. 3-20 | US11406644, Example 3-20 | ...)
Affinity DataIC50:  0.900nMAssay Description:Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Genzyme

US Patent
LigandPNGBDBM164912(US10166239, Ex. 3-20 | US11406644, Example 3-20 | ...)
Affinity DataIC50:  0.900nMAssay Description:Reagents and consumables were purchased from Sigma Aldrich, Carna Biosciences, or Caliper Life Sciences. All assay reaction conditions for IC50 deter...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Genzyme

US Patent
LigandPNGBDBM164912(US10166239, Ex. 3-20 | US11406644, Example 3-20 | ...)
Affinity DataIC50:  0.900nMAssay Description:In a 384 well polypropylene plate, TrkA (0.4 nM, Carna 08-186) was pre-incubated in a 100 mM Hepes-NaOH pH 7.5 buffer containing 0.01% Triton X-100, ...More data for this Ligand-Target Pair
In DepthDetails US Patent