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Found 4 Enz. Inhib. hit(s) with Target = 'Histamine H4 receptor' and Ligand = 'BDBM50304527'
TargetHistamine H4 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50304527(CHEMBL492677 | N4-Benzyl-6-(4-methylpiperazin-1-yl...)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50304527(CHEMBL492677 | N4-Benzyl-6-(4-methylpiperazin-1-yl...)
Affinity DataKi:  98nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai2 and Gbeta1gamma2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50304527(CHEMBL492677 | N4-Benzyl-6-(4-methylpiperazin-1-yl...)
Affinity DataEC50:  63nMAssay Description:Agonist activity at histamine H4 receptor (unknown origin) expressed in human U2OS cells increase in beta-arrestin2 recruitment after 2 hrs by lumine...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50304527(CHEMBL492677 | N4-Benzyl-6-(4-methylpiperazin-1-yl...)
Affinity DataEC50:  13nMAssay Description:Agonist activity at histamine H4 receptor (unknown origin) expressed in HEK293T cells harboring CRE-luciferase after 6 hrs by luciferase reporter gen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed