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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histone chaperone ASF1A' and Ligand = 'BDBM50101685'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histone chaperone ASF1A


(Homo sapiens)
BDBM50101685
PNG
(CHEMBL3394913)
Show SMILES COc1cc(\C=N\NC(=O)c2ccc(NC(=O)c3ccccc3)cc2)ccc1OCCN1CCCC1
Show InChI InChI=1S/C28H30N4O4/c1-35-26-19-21(9-14-25(26)36-18-17-32-15-5-6-16-32)20-29-31-28(34)23-10-12-24(13-11-23)30-27(33)22-7-3-2-4-8-22/h2-4,7-14,19-20H,5-6,15-18H2,1H3,(H,30,33)(H,31,34)/b29-20+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 1.00E+4n/an/an/an/an/an/a



Colorado State University

Curated by ChEMBL


Assay Description
Inhibition of His-tagged human Asf1a binding with H3/H4 assessed as fluorescence intensity after 30 mins by ALPHA assay


Bioorg Med Chem Lett 25: 963-8 (2015)


Article DOI: 10.1016/j.bmcl.2014.11.067
BindingDB Entry DOI: 10.7270/Q2VM4F0G
More data for this
Ligand-Target Pair