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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histone chaperone ASF1A' and Ligand = 'BDBM50101746'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histone chaperone ASF1A


(Homo sapiens)
BDBM50101746
PNG
(CHEMBL3394891)
Show SMILES COc1cc(\C=N\NC(=O)c2ccc(NC(=O)CCl)cc2)cc(Br)c1O
Show InChI InChI=1S/C17H15BrClN3O4/c1-26-14-7-10(6-13(18)16(14)24)9-20-22-17(25)11-2-4-12(5-3-11)21-15(23)8-19/h2-7,9,24H,8H2,1H3,(H,21,23)(H,22,25)/b20-9+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.20E+4n/an/an/an/an/an/a



Colorado State University

Curated by ChEMBL


Assay Description
Inhibition of His-tagged human Asf1a binding with H3/H4 assessed as fluorescence intensity after 30 mins by ALPHA assay


Bioorg Med Chem Lett 25: 963-8 (2015)


Article DOI: 10.1016/j.bmcl.2014.11.067
BindingDB Entry DOI: 10.7270/Q2VM4F0G
More data for this
Ligand-Target Pair