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Found 2 Enz. Inhib. hit(s) with Target = 'Histone deacetylase 8' and Ligand = 'BDBM50248376'
TargetHistone deacetylase 8(Homo sapiens (Human))
Mei Pharma

US Patent
LigandPNGBDBM50248376(3-(1-ethyl-2-phenethyl-1H-benzo[d]imidazol-5-yl)-N...)
Affinity DataIC50:  148nMMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Mei Pharma

US Patent
LigandPNGBDBM50248376(3-(1-ethyl-2-phenethyl-1H-benzo[d]imidazol-5-yl)-N...)
Affinity DataIC50:  148nMAssay Description:To determine EC50 where acetylated histone 3 was induced by 50%, Colo205 cells was cultivated in 96 well plate at 1.5×105 cells/well for 24 h. Colo20...More data for this Ligand-Target Pair
In DepthDetails US Patent