Found 11 Enz. Inhib. hit(s) with Target = 'Histone-lysine N-methyltransferase EZH2' and Ligand = 'BDBM50193709'
Affinity DataKi: 0.700nMAssay Description:Inhibition of wild-type EZH2 (unknown origin) expressed in baculovirus infected SF9 cells co-expressing SUZ12/EED/RbAp48 complex using HeLa cells der...More data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Binding affinity to EZH2 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of wild type EZH2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Inhibition of EZH2 Y641N mutant (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of wild type EZH2 Y641N mutant (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of EZH2 (unknown origin) using 3H-SAM as substrate incubated for 1 hour by filter binding methodMore data for this Ligand-Target Pair
Affinity DataIC50: <5nMAssay Description:Inhibition of EZH2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of EZH2 in human KARPAS422 cells assessed as reduction in H3K27Me3 levels after 72 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of EZH2 in HEK293T cells assessed as H3K27me3 levels incubated for 48 hrs by flow cytometryMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of EZH2 in human KARPAS422 cells assessed as reduction in H3K27me3 level after 72 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of wild type EZH2 in human KARPAS-422 cells assessed as effect on H3K27Me3 levelsMore data for this Ligand-Target Pair