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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Hypoxia-inducible factor prolyl hydroxylase 4 (HIF)' and Ligand = 'BDBM50000407'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hypoxia-inducible factor prolyl hydroxylase 4 (HIF)


(Homo sapiens (Human))
BDBM50000407
PNG
(2-carboxypyridine | CHEMBL72628 | alpha-picolinic ...)
Show SMILES OC(=O)c1ccccn1
Show InChI InChI=1S/C6H5NO2/c8-6(9)5-3-1-2-4-7-5/h1-4H,(H,8,9)
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
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CHEMBL
KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

Article
PubMed
n/an/a 1.00E+5n/an/an/an/an/an/a



ICI Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of prolyl 4-hydroxylase


J Med Chem 35: 800-4 (1992)


Article DOI: 10.1021/jm00083a001
BindingDB Entry DOI: 10.7270/Q25T3M3C
More data for this
Ligand-Target Pair
Hypoxia-inducible factor prolyl hydroxylase 4 (HIF)


(Homo sapiens (Human))
BDBM50000407
PNG
(2-carboxypyridine | CHEMBL72628 | alpha-picolinic ...)
Show SMILES OC(=O)c1ccccn1
Show InChI InChI=1S/C6H5NO2/c8-6(9)5-3-1-2-4-7-5/h1-4H,(H,8,9)
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
Purchase

CHEMBL
KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

Article
PubMed
n/an/a 1.12E+5n/an/an/an/an/an/a



Zeneca Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of prolyl 4-hydroxylase by chromatographic determination of [14C]-succinic acid on ion-exchange minicolumna


J Med Chem 36: 3853-8 (1994)


Article DOI: 10.1021/jm00076a014
BindingDB Entry DOI: 10.7270/Q2RJ4HJV
More data for this
Ligand-Target Pair