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Found 1 hit Enz. Inhib. hit(s) with Target = 'Hypoxia-inducible factor prolyl hydroxylase 4 (HIF)' and Ligand = 'BDBM50000416'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hypoxia-inducible factor prolyl hydroxylase 4 (HIF)


(Homo sapiens (Human))
BDBM50000416
PNG
(5-(Naphthalene-1-sulfonylaminocarbonyl)-pyridine-2...)
Show SMILES OC(=O)c1ccc(cn1)C(=O)NS(=O)(=O)c1cccc2ccccc12
Show InChI InChI=1S/C17H12N2O5S/c20-16(12-8-9-14(17(21)22)18-10-12)19-25(23,24)15-7-3-5-11-4-1-2-6-13(11)15/h1-10H,(H,19,20)(H,21,22)
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 4.40E+3n/an/an/an/an/an/a



ICI Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of prolyl 4-hydroxylase


J Med Chem 35: 800-4 (1992)


Article DOI: 10.1021/jm00083a001
BindingDB Entry DOI: 10.7270/Q25T3M3C
More data for this
Ligand-Target Pair