BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Indoleamine 2,3-dioxygenase 1' and Ligand = 'BDBM50324699'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Indoleamine 2,3-dioxygenase 1


(Homo sapiens (Human))
BDBM50324699
PNG
(CHEMBL1221473 | Seco-exiguamine)
Show SMILES CN(C)CCc1ccc(O)c(O)c1C1=C(c2c(O)n(C)c(=O)n2C)C(=O)c2c(CCN)c[nH]c2C1=O
Show InChI InChI=1S/C25H29N5O6/c1-28(2)10-8-12-5-6-14(31)21(32)15(12)17-18(20-24(35)30(4)25(36)29(20)3)22(33)16-13(7-9-26)11-27-19(16)23(17)34/h5-6,11,27,31-32,35H,7-10,26H2,1-4H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
80n/an/an/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibition of human recombinant indoleamine-2,3-dioxygenase


Nat Chem Biol 4: 535-7 (2008)


Article DOI: 10.1038/nchembio.107
BindingDB Entry DOI: 10.7270/Q2P55NR5
More data for this
Ligand-Target Pair