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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)' and Ligand = 'BDBM50116133'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)


(Homo sapiens (Human))
BDBM50116133
PNG
((3-Methoxy-4-oxazol-5-yl-phenyl)-[4-(4-methyl-pipe...)
Show SMILES COc1cc(Nc2nc(nc(n2)-c2ccccc2)N2CCN(C)CC2)ccc1-c1cnco1
Show InChI InChI=1S/C24H25N7O2/c1-30-10-12-31(13-11-30)24-28-22(17-6-4-3-5-7-17)27-23(29-24)26-18-8-9-19(20(14-18)32-2)21-15-25-16-33-21/h3-9,14-16H,10-13H2,1-2H3,(H,26,27,28,29)
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Article
PubMed
n/an/a 330n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human Inosine-5'-monophosphate dehydrogenase 2


Bioorg Med Chem Lett 12: 2137-40 (2002)


Article DOI: 10.1016/s0960-894x(02)00351-7
BindingDB Entry DOI: 10.7270/Q2NZ86Z7
More data for this
Ligand-Target Pair