Compile Data Set for Download or QSAR
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Found 5 Enz. Inhib. hit(s) with Target = 'Integrin alpha-IIb/beta-3' and Ligand = 'BDBM50003851'
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50003851((6S,12S,15S)-1,6-diamino-15-benzyl-12-(carboxymeth...)
Affinity DataIC50:  31nMAssay Description:Inhibition of Fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50003851((6S,12S,15S)-1,6-diamino-15-benzyl-12-(carboxymeth...)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of Fibrinogen receptor bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50003851((6S,12S,15S)-1,6-diamino-15-benzyl-12-(carboxymeth...)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of platelet aggregation (PRP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50003851((6S,12S,15S)-1,6-diamino-15-benzyl-12-(carboxymeth...)
Affinity DataIC50:  4.30E+4nMAssay Description:Inhibition of ADP-induced platelet aggregation in human platelet-rich plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50003851((6S,12S,15S)-1,6-diamino-15-benzyl-12-(carboxymeth...)
Affinity DataIC50:  7.25E+5nMAssay Description:Inhibition of fibrinogen binding to human alpha2b/beta3 integrin after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed