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Found 4 Enz. Inhib. hit(s) with Target = 'Integrin alpha-IIb/beta-3' and Ligand = 'BDBM50006271'
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50006271(15-(2-Carboxy-ethyl)-6-carboxymethyl-12-(3-guanidi...)
Affinity DataIC50:  4.70nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50006271(15-(2-Carboxy-ethyl)-6-carboxymethyl-12-(3-guanidi...)
Affinity DataIC50:  4.70nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50006271(15-(2-Carboxy-ethyl)-6-carboxymethyl-12-(3-guanidi...)
Affinity DataIC50:  900nMAssay Description:Inhibition of ADP-induced platelet aggregation in human platelet-rich plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50006271(15-(2-Carboxy-ethyl)-6-carboxymethyl-12-(3-guanidi...)
Affinity DataIC50:  900nMAssay Description:Inhibition of ADP-induced platelet aggregation in human platelet-rich plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed