Compile Data Set for Download or QSAR
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Found 4 Enz. Inhib. hit(s) with Target = 'Integrin alpha-IIb/beta-3' and Ligand = 'BDBM50040751'
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals Research And Development

Curated by ChEMBL
LigandPNGBDBM50040751(CHEMBL351938 | [(4S,7S,13R,16S)-16-Acetylamino-4-c...)
Affinity DataKi:  720nMAssay Description:Inhibition of 125[I] Fibrinogen binding to isolated purified human fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals Research And Development

Curated by ChEMBL
LigandPNGBDBM50040751(CHEMBL351938 | [(4S,7S,13R,16S)-16-Acetylamino-4-c...)
Affinity DataKi: >1.00E+6nMAssay Description:Tested for inhibition of fibrinogen binding to purified GPIIb/IIIa isolated from human platelets and reconstituted in liposomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals Research And Development

Curated by ChEMBL
LigandPNGBDBM50040751(CHEMBL351938 | [(4S,7S,13R,16S)-16-Acetylamino-4-c...)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of canine platelet-rich plasma agregation induced by ADPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals Research And Development

Curated by ChEMBL
LigandPNGBDBM50040751(CHEMBL351938 | [(4S,7S,13R,16S)-16-Acetylamino-4-c...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of canine platelet-rich plasma agregation induced by ADPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed