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Found 2 Enz. Inhib. hit(s) with Target = 'Integrin alpha-IIb/beta-3' and Ligand = 'BDBM50078439'
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50078439((S)-2-Methanesulfonylamino-3-{[5-(2-piperidin-4-yl...)
Affinity DataIC50:  15nMAssay Description:The compound was tested in vivo for the inhibition of aggregation of human gel-filtered platelets(GFP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50078439((S)-2-Methanesulfonylamino-3-{[5-(2-piperidin-4-yl...)
Affinity DataKd:  52nMAssay Description:Displacement of L-762,745 from Fibrinogen Receptor of human platelets by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed