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Found 4 Enz. Inhib. hit(s) with Target = 'Integrin alpha-IIb/beta-3' and Ligand = 'BDBM50155250'
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
A.V. Bogatsky Physico-Chemical Institute Of The National Academy Of Sciences Of Ukraine

Curated by ChEMBL
LigandPNGBDBM50155250(3-[3-(2,3-Dihydro-1H-isoindol-5-ylcarbamoyl)-propi...)
Affinity DataKi:  4.20nMAssay Description:In vitro binding affinity for FITC-labeled fibrinogen binding to alphaIIb-beta3 receptor of human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
A.V. Bogatsky Physico-Chemical Institute Of The National Academy Of Sciences Of Ukraine

Curated by ChEMBL
LigandPNGBDBM50155250(3-[3-(2,3-Dihydro-1H-isoindol-5-ylcarbamoyl)-propi...)
Affinity DataIC50:  8.30nMAssay Description:In vitro inhibition of FITC-labeled fibrinogen binding to alphaIIb-beta3 receptor of human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
A.V. Bogatsky Physico-Chemical Institute Of The National Academy Of Sciences Of Ukraine

Curated by ChEMBL
LigandPNGBDBM50155250(3-[3-(2,3-Dihydro-1H-isoindol-5-ylcarbamoyl)-propi...)
Affinity DataIC50:  270nMAssay Description:In vitro inhibition of human platelet aggregation in suspensionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
A.V. Bogatsky Physico-Chemical Institute Of The National Academy Of Sciences Of Ukraine

Curated by ChEMBL
LigandPNGBDBM50155250(3-[3-(2,3-Dihydro-1H-isoindol-5-ylcarbamoyl)-propi...)
Affinity DataIC50:  860nMAssay Description:In vitro inhibition of human platelet aggregation in platelet rich plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed