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Found 2 Enz. Inhib. hit(s) with Target = 'Interleukin-1 receptor-associated kinase 1' and Ligand = 'BDBM50040733'
TargetInterleukin-1 receptor-associated kinase 1(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM50040733(CHEMBL3353215 | US10064861, Compound 20)
Affinity DataIC50: <100nMpH: 7.0Assay Description:IRAK1 is a human purified recombinant enzyme (His-TEV-IRAK1 (194-712)) In this assay, IRAK-1 hydrolyses ATP and autophosphorylates.Measurement of IRA...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 1(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM50040733(CHEMBL3353215 | US10064861, Compound 20)
Affinity DataIC50: <100nMAssay Description:Inhibition of IRAK1 (unknown origin) by radiochemical assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed