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Found 3 Enz. Inhib. hit(s) with Target = 'Interleukin-1 receptor-associated kinase 4' and Ligand = 'BDBM50095475'
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50095475(CHEMBL3590479)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of human IRAK4 assessed as phosphorylation of fluorescent peptide substrate after 30 mins by fluorescent polarization readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50095475(CHEMBL3590479)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50095475(CHEMBL3590479)
Affinity DataIC50:  4nMAssay Description:Inhibition of IRAK4 in human PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed