Compile Data Set for Download or QSAR
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Found 3 Enz. Inhib. hit(s) with Target = 'Interleukin-1 receptor-associated kinase 4' and Ligand = 'BDBM50130669'
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50130669(CHEMBL3634614 | US10329295, Example 35)
Affinity DataIC50:  1nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50130669(CHEMBL3634614 | US10329295, Example 35)
Affinity DataIC50:  1nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50130669(CHEMBL3634614 | US10329295, Example 35)
Affinity DataIC50:  25nMAssay Description:Inhibition of IRAK4 in human PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed