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Found 2 Enz. Inhib. hit(s) with Target = 'Interleukin-1 receptor-associated kinase 4' and Ligand = 'BDBM50502737'
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM50502737(CHEMBL4441283 | US11065231, Example 58)
Affinity DataIC50: <30nMAssay Description:A Z′-Lyte assay based on a fluorescence resonance energy transfer (FRET) readout was developed for measuring IRAK4-dependent phosphorylation of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM50502737(CHEMBL4441283 | US11065231, Example 58)
Affinity DataIC50: <30nMAssay Description:Inhibition of N-terminal GST-tagged human IRAK4 (2 to end residues) expressed in baculovirus infected Sf9 cells using Ser/Thr 7 peptide as substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed