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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Kaposi's sarcoma-associated herpesvirus protease (KSHV Pr)' and Ligand = 'BDBM36460'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Kaposi's sarcoma-associated herpesvirus protease (KSHV Pr)


(Human herpesvirus 8)
BDBM36460
PNG
(3-Benzyl-4-(6-(cyclohexylmethyl)picolinamido)benzo...)
Show SMILES OC(=O)c1ccc(NC(=O)c2cccc(CC3CCCCC3)n2)c(Cc2ccccc2)c1
Show InChI InChI=1S/C27H28N2O3/c30-26(25-13-7-12-23(28-25)17-20-10-5-2-6-11-20)29-24-15-14-21(27(31)32)18-22(24)16-19-8-3-1-4-9-19/h1,3-4,7-9,12-15,18,20H,2,5-6,10-11,16-17H2,(H,29,30)(H,31,32)
MMDB

KEGG

UniProtKB/SwissProt

GoogleScholar
MMDB
PC cid
PC sid
PDB
UniChem
Article
PubMed
n/an/a 1.50E+3n/an/an/an/a8.0n/a



University of California at San Francisco



Assay Description
Compounds were prepared in 100% DMSO from 10 to 0.156 mM and/or from 5 to 0.078 mM. The P6 substrate concentrations were 5, 65, and 150 ÁM for KSHV, ...


Biochemistry 53: 4648-60 (2014)


Article DOI: 10.1021/bi5003234
BindingDB Entry DOI: 10.7270/Q2WH2NQW
More data for this
Ligand-Target Pair