Affinity DataKi: 0.0430nMAssay Description:Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cell membrane by liquid scintillation and luminescence counterMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Compound was evaluated for binding affinity against [3H]- U-69593 labeled kappa1 opioid receptor in guinea-pig brain homogenate.More data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Compound was evaluated for kappa opioid receptor mediated agonistic effect in electrically stimulated guinea-pig ileumMore data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Compound was evaluated for kappa opioid receptor mediated agonistic effect in electrically stimulated guinea-pig ileumMore data for this Ligand-Target Pair
Affinity DataIC50: 5.60nMAssay Description:Compound was evaluated for kappa opioid receptor mediated agonistic effect in mouse vas deferens(MVD) preparationsMore data for this Ligand-Target Pair
Affinity DataEC50: 0.120nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cell membrane assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair