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Found 4 Enz. Inhib. hit(s) with Target = 'Kappa-type opioid receptor' and Ligand = 'BDBM50265525'
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM50265525(CHEMBL4092454)
Affinity DataKi:  155nMAssay Description:Displacement of 3H-U69593 from human KOR expressed in HEK293 cells after 90 mins by micro beta scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM50265525(CHEMBL4092454)
Affinity DataKi:  160nMAssay Description:Displacement of 3H-U69593 from human KOR expressed in HEK293 cells after 90 mins by micro beta scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM50265525(CHEMBL4092454)
Affinity DataEC50:  8.10E+3nMAssay Description:Agonist activity at KOR (unknown origin) expressed in HTLA cells assessed as beta-arrestin recruitment incubated overnight by Bright-Glo luminescence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Southern California

Curated by ChEMBL
LigandPNGBDBM50265525(CHEMBL4092454)
Affinity DataEC50:  530nMAssay Description:Antagonist activity at human KOR expressed in HEK293T cells coexpressing Gi assessed as Gi-mediated inhibition of cAMP production incubated for 15 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed