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Found 9 Enz. Inhib. hit(s) with Target = 'KiSS-1 receptor' and Ligand = 'BDBM50442961'
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50442961(CHEMBL3086284)
Affinity DataKi:  0.0890nMAssay Description:Binding affinity to human KISS1R expressed in CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50442961(CHEMBL3086284)
Affinity DataKi:  0.100nMAssay Description:Binding affinity to rat KISS1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50442961(CHEMBL3086284)
Affinity DataKi:  0.110nMAssay Description:Displacement of radioligand from human KISS1R transfected in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50442961(CHEMBL3086284)
Affinity DataKi:  0.140nMAssay Description:Displacement of radioligand from rat KISS1R transfected in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50442961(CHEMBL3086284)
Affinity DataIC50:  8.90nMAssay Description:Inhibition of human KISS1R expressed in CHO cells assessed as inhibition of KISS1R-mediated cell growth after 4 days by cell counting kit-8 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50442961(CHEMBL3086284)
Affinity DataEC50:  10nMAssay Description:Agonist activity at rat KISS1R transfected in CHO cells assessed as intracellular calcium flux after 24 hrs by functional FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50442961(CHEMBL3086284)
Affinity DataEC50:  2.60nMAssay Description:Agonist activity at human KISS1R transfected in CHO cells assessed as intracellular calcium flux after 24 hrs by functional FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Rattus norvegicus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50442961(CHEMBL3086284)
Affinity DataEC50:  0.170nMAssay Description:Agonist activity at rat KISS1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKiSS-1 receptor(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50442961(CHEMBL3086284)
Affinity DataEC50:  0.270nMAssay Description:Agonist activity at human KISS1R expressed in CHO cells assessed as increase in calcium mobilization measured at 2 secs interval for 2 mins by fluo-4...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed