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Found 6 Enz. Inhib. hit(s) with Target = 'LIM domain kinase 1' and Ligand = 'BDBM50072664'
TargetLIM domain kinase 1(Homo sapiens (Human))
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50072664(CHEMBL3410036)
Affinity DataIC50:  43nMAssay Description:Inhibition of LIMK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetLIM domain kinase 1(Homo sapiens (Human))
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50072664(CHEMBL3410036)
Affinity DataIC50:  43nMAssay Description:Inhibition of human Limk1 using cofilin substrate, ATP and [gamma33P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLIM domain kinase 1(Homo sapiens (Human))
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50072664(CHEMBL3410036)
Affinity DataIC50:  372nMAssay Description:Inhibition of recombinant LIMK1 (330 to 637 residues) (unknown origin) incubated for 45 mins followed by ATP addition measured after 105 mins by Rapi...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetLIM domain kinase 1(Rattus norvegicus)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50072664(CHEMBL3410036)
Affinity DataIC50:  470nMAssay Description:Inhibition of Limk1 in rat A7r5 cells assessed as reduction in cofilin phosphorylation by Western blot methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLIM domain kinase 1(Homo sapiens (Human))
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50072664(CHEMBL3410036)
Affinity DataIC50:  741nMAssay Description:Inhibition of recombinant LIMK1(unknown origin) expressed in HEK293 cells using NanoGlo substrate incubated for 2 hrs followed by substrate addition ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetLIM domain kinase 1(Homo sapiens (Human))
Johann Wolfgang Goethe-University

Curated by ChEMBL
LigandPNGBDBM50072664(CHEMBL3410036)
Affinity DataIC50:  2.04E+3nMAssay Description:Inhibition of PAK mediated recombinant LIMK1 phosphorylation (330 to 637 residues) (unknown origin) incubated for 45 mins followed by ATP addition me...More data for this Ligand-Target Pair
In DepthDetails PubMed