Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Lysine-specific histone demethylase 1A' and Ligand = 'BDBM504315'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM504315 (N-(37-oxo-39-(4'-((trans)-2- | US11034991, Example...) Show SMILES O=C(CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)CCc1cccc(c1)-c1ccc(cc1)[C@@H]1C[C@H]1NC1CCNCC1 Show InChI InChI=1S/C57H92N6O14S/c64-54(7-2-1-6-53-56-52(44-78-53)62-57(66)63-56)59-18-20-67-22-24-69-26-28-71-30-32-73-34-36-75-38-40-77-41-39-76-37-35-74-33-31-72-29-27-70-25-23-68-21-19-60-55(65)13-8-45-4-3-5-48(42-45)46-9-11-47(12-10-46)50-43-51(50)61-49-14-16-58-17-15-49/h3-5,9-12,42,49-53,56,58,61H,1-2,6-8,13-41,43-44H2,(H,59,64)(H,60,65)(H2,62,63,66)/t50-,51+,52-,53-,56-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	126	n/a	n/a	n/a	n/a	n/a	n/a
Oryzon Genomics S.A. US Patent					Assay Description KDM1A inhibition assay: a multistep enzymatic reaction in which the enzyme first produces H2O2 during the demethylation of lysine 4 in a 21 AA H3K4me...				US Patent US11034991 (2021)
					More data for this Ligand-Target Pair